Professor Stephen Worthley graduated from Medicine at the Adelaide University. His training included his Cardiology fellowship at the Royal Adelaide Hospital, his PhD at the Mount Sinai Medical Centre in New York, and post-doctoral fellowship at Monash Medical Centre, Melbourne. He established the first dedicated Cardiac CT and MR units in the Asia Pacific region, as well as leading the Cardiovascular Research Centre at the University of Adelaide as the Helpman Professor of Cardiovascular Medicine, a position he held between 2004 to 2016.

 He has published over 230 manuscripts, 5 book chapters, and co-edited a Cardiovascular Textbook. He leads a number of novel international multi-centre cardiovascular therapy trials, and his clinical and research expertise has included stem cell therapy, cardiac MRI and cardiovascular CT, transcatheter valve replacement, percutaneous mitral valve therapies and renal artery denervation therapy. He has led and performed many first-in-human cardiovascular devices. He sits on numerous industry advisory boards, journal editorial boards and government advisory groups.